Using this approach, we generated complete tail fiber models, validated by single-particle cryo–electron microscopy of
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These techniques cannot be used to examine individual interactions between a singular set of a phage''s adsorptive
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RBPseg is a pipeline designed to predict and analyze phage tail fiber proteins. It has three major modules.
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Viral fibers play a central role in many virus infection mechanisms since they recognize the corresponding host and establish a
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Tail fibers are disordered in the cryoEM structures, as they represent the average of many particles each having the fibers in a
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While the V22 chaperone is essential for producing active tail fibers, here we demonstrate production of functional A5
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A critical component of bacterial detection assays is choosing a suitable affinity molecule that retains sensitivity and
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The fraction modules can be merged together into a full fiber structure. RBPseg also has a built structural clustering metric (SM/pSM)
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Abstract A colorimetric detection method for Escherichia coli (E. coli) in water was established based on a T7 phage tail fiber protein
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Using this approach, we generated complete tail fiber models, validated by single- particle cryo–electron microscopy of five fibers
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Recent significant advances at single-molecule and atomic levels have begun to unravel the
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Structural comparisons of the tail tips, the most diversified region across the lambda and other long-tailed phages or tail-like
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The complicated nature of fiber structures necessitates the participation of intra- or intermolecular chaperones for their
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In this paper, we introduce RBPseg, a method that combines monomeric ESMfold predictions with a novel sigmoid
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Here, we introduce RBPseg, a method that combines monomeric ESMFold predictions with a structural-based domain identification
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Furthermore, phage tail fibers with confirmed, or potential, depolymerase activity, but no functional domain hits, were
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A collaborative project between Charley Peters, Wesley Goatley and Tobias Revell. Charismatic Megapigment is a
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The whiskers (also called short tail fibers) are responsible for an irreversible interaction: upon receptor binding, a recognition signal
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RBPseg enables accurate modeling of tail fiber structure, providing the first comprehensive tail fiber structure atlas.
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